Lay Summaries

The search for measurable predictors linked with safe and effective response to treatment in psoriasis

The search for measurable predictors linked with safe and effective response to treatment in psoriasis

Psoriasis is a common, non-contagious, long-term, inflammatory skin condition affecting approximately two in every 100 people. People who have psoriasis suffer from uncomfortable, red scaly patches of skin which can have a significant negative impact...

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The search for measurable predictors linked with negative health complications in psoriasis

The search for measurable predictors linked with negative health complications in psoriasis

Psoriasis is a non-contagious, long-term, inflammatory skin condition that affects approximately two in every 100 people in the Western world. It causes uncomfortable, red scaly patches on the skin, and is also linked to associated conditions such as...

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Systematic review of ethical and social aspects of biomarker research and its application in atopic dermatitis and psoriasis

Systematic review of ethical and social aspects of biomarker research and its application in atopic dermatitis and psoriasis

Biomarker research is associated with high hopes for the two chronic skin diseases atopic dermatitis and psoriasis.

Although various effective treatments have been developed, many challenges remain concerning diagnostics (the practice of identif...

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Can we obtain genetic information from DNA without testing it directly?

Can we obtain genetic information from DNA without testing it directly?

Our DNA or genetic code controls how our bodies work in health and disease. This is because our genes spell out the codes for proteins – the building blocks of life.

One gene, called filaggrin, holds the code for a protein that helps to make skin a...

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Differences in the comorbidities experienced between HLA-C*06:02 carrier groups in 9,000 psoriasis patients

Differences in the comorbidities experienced between HLA-C*06:02 carrier groups in 9,000 psoriasis patients

Psoriasis is a very common skin condition with major impact on health and wellbeing. Unfortunately, some people also develop other health conditions (often termed ‘comorbidities’) such as arthritis and heart disease.

A person’s genetic make-up is a...

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People’s physical features, their lifestyle and the environment are associated with the skin bacteria

People’s physical features, their lifestyle and the environment are associated with the skin bacteria

Many bacteria, mostly harmless or beneficial, live on people’s skin. We know little about what influences these bacteria. Here, we studied the associations between people’s physical features, lifestyle and environment with the bacteria living on thei...

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